Twanisha Terry stormed home in the anchor leg to secure a gold medal for the USA in the women's 4x100m relay at the World Athletics Championships in Oregon.
While the Jamaicans - who include both the world 100m and 200m champions in their ranks - had been heavily tipped for the victory, they could only finish second as the US team delivered a memorable win on home soil.
Third place went to Germany with Great Britain finishing sixth after a mid-race injury to Dina Asher-Smith.
The USA sped out of the blocks, with Melissa Jefferson running the fastest split of 11.35 over the first 100m. She handed off to rising star Abby Steiner who outdid world record holder Elaine Thompson-Herah to keep her team in pole position.
And while Jackson gained on Terry over the last 100, it was not enough to catch the USA who can now celebrate another gold medal at these home World Championships.
Terry expressed her pride at having delivered the sprint relay gold at the first Worlds to take place on US soil in history
"The victory lap was amazing," she said, after soaking up the victory in front of the Hayward Field faithful. "To be able to feel the energy from the crowd, to shake hands, sign autographs.
"It's just an amazing feeling. The race was electrifying. You heard the stadium. The stadium went crazy. We just brought it home."
Steiner proclaimed the race to be the greatest she had experienced so far in her burgeoning track career.
"This is the most fun race of my life," she said. "You can hear my voice. I never scream that loud during a race. Hayward magic is a real thing."
And Jefferson, who won a surprise 100m title at this year's national championships, pointed to the shock nature of this win, as the US team rose victorious in a race few had predicted them winning.
"It was not expected of us today and I am glad we pulled it through," she said. "Our teammates and I have a lot of confidence in ourselves and I knew we would show the world what we are capable of."