Winners of recent majors will tee it up at Kasumigaseki Country Club as the USA bids to add to its haul of one medal from Rio.
Matt Kuchar won bronze in the men's event at Rio 2016, but hopes are high for more with Collin Morikawa arriving on the back of his second major triumph at the Open Championship.
USA also boasts a recent winner of a women's major in Nelly Korda who claimed the Women's PGA Championship title in June to go top of the world rankings.
Korda sisters in medal hunt
It could be Korda v Korea for gold in Tokyo.
South Korean women have dominated golf in recent years, and Nelly Korda's maiden major triumph in June's Women's PGA Championship was the first for an American since Angela Stanford at the 2018 Evian Championship
Big sister Jessica, who has also made the USA Olympic team, was the first to congratulate her in Atlanta.
That win saw Nelly become the first player from outside Asia and Australasia to take the world number one spot since Stacy Lewis in 2014.
That came the week after she won the Meijer LPGA Classic with the 22-year-old also taking the Gainbridge LPGA event in late February.
Jessica, who has been on the fringes of the top 10 for most of the year, took the last US spot behind major winners Danielle Kang and Rio 2016 Olympian Lexi Thompson.
Nelly is the only member of the team with titles to her name this season, and much will be expected of her in Tokyo.
Success is certainly not new to the Kordas with their tennis-playing father Petr winning the Australian Open back in 1998.
Both sisters have now won the golf equivalent with younger brother Sebastian, who chose racquets over clubs but turned down his spot in Tokyo to focus on the US Open, taking the junior Australia Open title.
All of them celebrated with Dad's trademark scissor kick.
Morikawa leads men's hopes
For the second Games running, the United States is the only country with four men going for gold.
Spain's Jon Rahm may be the world number one with number two Dustin Johnson opting out of Tokyo, but the USA team comprises the next four in the rankings.
After winning on his Open Championship debut at Royal St George's, Collin Morikawa is up to a career-high three in the world and setting about becoming one of the greats of the sport.
The 24-year-old Californian only turned professional two years ago after completing a business administration degree at the University of California, Berkeley.
Now he has two major titles in eight starts, and would love to add Olympic gold to his growing list of accolades, as he announced on the Tonight Show with Jimmy Fallon.
A lifelong LA Dodgers baseball fan and breakfast fanatic - he has cereal names and bacon engraved on his wedges - Morikawa has been with his coach Rick Sessinghaus since the age of eight.
Sessinghaus, who has a doctorate in applied psychology, has helped Morikawa develop an enviable calmness in pressure situations as shown in both his major triumphs.
In his first at the 2020 PGA Championship, he shot weekend rounds of 65 and 64 for the lowest closing 36-hole score in major history.
Then last week, he carded a blemish-free four-under-par 66 final round to claim the claret jug on his first attempt.
Justin Thomas is down to four in the world following something of a slump after his PLAYERS Championship success in March.
The man from Kentucky has just the one major to his name - the 2017 PGA Championship - and he will need to rediscover his touch with the putter if he is to be competitive.
Xander Schauffele and 2020 US Open champ Bryson DeChambeau complete the team with the former seeking his first win since last September's TOUR Championship.
Big-hitting DeChambeau was tie for third behind Thomas in the PLAYERS, a week after his last victory at the Arnold Palmer Invitational.
While his feud with four-time major winner Brooks Koepka has made more headlines than his play in recent months, gym rat DeChambeau will be looking to bring his 'A' game to Kasumigaseki Country Club and perhaps collect a medal.